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Imagerie 3D d'élasticité du Sein Par échographie Ultrarapide au Cours d'un Traitement Par chimiothérapie néoadjuvante.


N/A
18 Years
75 Years
Open (Enrolling)
Female
Malignant Breast Tumours

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Trial Information

Imagerie 3D d'élasticité du Sein Par échographie Ultrarapide au Cours d'un Traitement Par chimiothérapie néoadjuvante.


3D breast ultrasound elastography provides volumetric lesion stiffness details in real time.
3D acquisition is compared to breast MRI in order to evaluate volume measurements calculated
in ultrasound. Lesion elasticity is calculated in 3 planes with immediate reconstruction.
The purpose of this prospective study is to evaluate the feasibility of this technique and
compare the results to those of Breast MRI. For women receiving preoperative chemotherapy,
this technique will be evaluated with regard to tumour shrinkage and lesion elasticity
modifications under treatment.


Inclusion Criteria:



- Patients having already undergone a breast MRI

- Patients presenting with breast lesions measuring between20-50mm in ultrasound

Exclusion Criteria:

- Multifocal lesions

- History of breast cancer

- Breast implants

- Inflammatory breast disease

- Pregnancy

Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

3D volumetric elasticity measurements

Outcome Description:

An utrafast shear wave imaging 3-plane acquisition provides several frames of breast lesion elasticity, that are reconstructed by means of a dedicated software thus permitting the direct volumetric elasticity measurements in kPa

Outcome Time Frame:

10min

Safety Issue:

No

Principal Investigator

Alexandra Athanasiou, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Curie Cancer Institute

Authority:

France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Study ID:

C10-02

NCT ID:

NCT01531036

Start Date:

December 2010

Completion Date:

September 2013

Related Keywords:

  • Malignant Breast Tumours
  • Breast Neoplasms

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