Trial Information

Using New Approaches for Genomics Studies in Pediatric Adrenocortical Tumors: Whole Genome Sequencing; Deep Sequencing; miRNA; methDNA and SNP 6.0

OBJECTIVES:

- To perform whole-genome sequencing, deep sequencing, micro RNA analysis, methylation
status, copy number variation analysis, and single-nucleotide polymorphisms (SNPs)
analysis in pediatric adrenocortical tumors and compare those results to those of the
same patient's normal cells.

OUTLINE: Archived tumor and blood samples are analyzed for whole-genome sequencing, deep
sequencing, micro RNA , methylation status, copy variation, and single-nucleotide
polymorphisms. Results are then compared with patients' normal cells.