Monitoring and Analysis of Gene Expression, Immunological Status and Metabolome in Peripheral Blood Mononuclear Cells and Their Specific Subpopulations (CD4+ T Cells and CD56+ NK Cells) in Surgically Treated Glioma Patients
N/A
20 Years
80 Years
20 Years
80 Years
Open (Enrolling)
Both
Glioma
Both
Glioma
Trial Information
Monitoring and Analysis of Gene Expression, Immunological Status and Metabolome in Peripheral Blood Mononuclear Cells and Their Specific Subpopulations (CD4+ T Cells and CD56+ NK Cells) in Surgically Treated Glioma Patients
Inclusion Criteria:
- malignant glioma = glioblastoma (WHO IV) patients
Exclusion Criteria:
- pregnancy
- metastases
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Transcriptome profile of CD4+ T and CD56+ NK cells
Outcome Time Frame:
within 10 days before surgery
Safety Issue:
No
Principal Investigator
Tamara Lah Turnšek, PhD
Investigator Role:
Study Chair
Investigator Affiliation:
National Institute of Biology, Ljubljana, Slovenia
Authority:
Slovenia: Ethics Committee
Study ID:
MNC-Glioma-1-4
NCT ID:
NCT01525459
Start Date:
December 2010
Completion Date:
December 2012
Related Keywords:
- Glioma
- Glioma
- PBMC subpopulations
- Gene expression
- Metabolomics
- Immunological status
- miRNA
- Proteomics
- Glioma
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