A Feasibility Study Using Four-Dimensional CT Imaging to Evaluate Lung Strain in Patients Treated With External Beam Radiation Therapy for Primary Lung Cancer
The study will be a prospective, non-randomized, single center, trial to assess and quantify
lung strain using 4D-CT treatment planning scans. Patients with newly diagnosed lung cancer
will be planned using 4D-CT to assess lung and tumor motion. Standard radiation treatment
plans will to delivered based on tumor stage. Patients will be reassessed both clinically
and radiographically using 4D-CT imaging at 3 months and 6 months post-treatment. Following
the initial imaging time points, standard surveillance will be employed with clinical
assessment and imaging at 3 month intervals for the first 2 years post-treatment.
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
validate lung strain modeling using 4D-CT in a lung cancer patient population to correlate pre-treatment strain with post-treatment changes.
The study will be a prospective, non-randomized, single center, trial to assess and quantify lung strain using 4D-CT treatment planning scans.
Pre-treatment (baseline) up to 6 months post-treatment
Neal E Dunlap, MD
James Graham Brown Cancer Center
United States: Institutional Review Board
|James Graham Brown Cancer Center||Louisville, Kentucky 40202|