Microarray Analysis of microRNA Expression in Basal Cell Carcinoma
Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a
variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been
systematically evaluated regarding differentially expressed miRNAs. Patients with BCC are
included in the study to perform an exploratory analysis by miRNA expression profiling using
microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time
quantitative polymerase chain reaction (RT-PCR).
Observational Model: Case Control, Time Perspective: Prospective
Falk G Bechara, PD Dr.
Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum
Germany: Ethics Commission