Inclusion Criteria:

1. Newly diagnosed prostate cancer pathologically proven by prostate biopsy

2. Prostate biopsy histology grade ≥ Gleason 4+3=7

3. Patients considered as candidates for and medically fit to undergo prostatectomy

4. At least 10 days after most recent prostate biopsy

5. No known problems with peripheral IV or central line access

6. Able to tolerate urinary straight catheter placement

7. Patient is judged by the Investigator to have the initiative and means to be
compliant with the protocol and be within geographical proximity to make the required
study visits.

8. Patients or their legal representatives must have the ability to read, understand and
provide written informed consent for the initiation of any study related procedures.

Exclusion Criteria:

1. Prior pelvic external beam radiation therapy or brachytherapy

2. Chemotherapy for prostate cancer

3. Hormone deprivation therapy

4. Investigational therapy for prostate cancer

5. Hemorrhagic cystitis or active prostatitis

6. Unable to lie flat during or tolerate PET/CT

7. Prior history of any other malignancy within last 2 years, other than skin basal cell
carcinoma.

8. No prostatectomy scheduled prior to follow-up visit (12 to 72 hours post imaging)

9. Serum creatinine > 1.5 mg/dL or creatinine clearance < 50 mL/min/1.73m2

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