Inclusion Criteria:

- Female patient with histologically proven breast cancer

- 18-76 years old

- Patients having undergone curative surgery and eligible to 6 cycles of adjuvant
chemotherapy (6 FEC100, or 3FEC100 + taxanes) followed by radiotherapy

- Satisfactory healing of breast and lymph nodes area

- Ability to understand the nature, goal and study methodology

- Consent to cooperate for clinical assessments

- Affiliation to a social security regime or beneficiary of equivalent social
protection

- Written informed consent provided before any study specific procedures

Exclusion Criteria:

- HER2 positive or metastatic cancer

- Any other primary tumor

- Contraindication to moderate physical activity

- Contraindication to adjuvant chemotherapy or radiotherapy

- Pregnancy or breast feeding

- Inability to attend or comply with interventions or follow-up scheduling, disability
or difficulty preventing a proper understanding of trial