The EC90 of Remifentanil Blunting Hemodynamic Changes to Head Fixation in the Patients Undergoing Neurosurgery
N/A
20 Years
65 Years
20 Years
65 Years
Not Enrolling
Both
Brain Tumor, AVM, ICH
Both
Brain Tumor, AVM, ICH
Trial Information
The EC90 of Remifentanil Blunting Hemodynamic Changes to Head Fixation in the Patients Undergoing Neurosurgery
Inclusion Criteria:
- patients undergoing neurosurgery that require head fixation with mayfield head holder
- patients who agree to our study
Exclusion Criteria:
- patients who don't agree to our study
- BMI<16.0 or BMI>30
- cardiovascular disease, pulmonary disease, renal disease
- alcoholic abuser or drug abuser
- patients who takes any drug having an influence on cardiovascular system or
sympathetic nervous system
- any use of local anesthetics or drugs which have an influence on cardiovascular
system from beginning of induction to peri-fixation period
Type of Study:
Interventional
Study Design:
Endpoint Classification: Pharmacodynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Outcome Measure:
mean arterial blood pressure
Outcome Description:
mean arterial blood pressure will be recorded at 2 minutes before fixation, 1 minute before fixation, highest value during immediately post-fixation periord, 1 minute after fixation, 2 minutes after fixation, 3 minutes after fixation, 4 minutes after fixation and 5 minutes after fixation.
Outcome Time Frame:
peri-fixation periord
Safety Issue:
No
Authority:
Korea: Food and Drug Administration
Study ID:
JHBahk_fixation_remifentanil
NCT ID:
NCT01489137
Start Date:
November 2011
Completion Date:
Related Keywords:
- Brain Tumor
- AVM
- ICH
- Brain Neoplasms
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