Trial Information
Feasibility of Gene Expression Profiling Using Low-volume Lung Aspirate
The investigators will compare results of mutational analysis from a core needle biopsy and
fine needle aspiration.
Inclusion Criteria:
- primary tumor or a metastatic lung lesion requested for mutational analysis
Exclusion Criteria:
- a) lesions located adjacent to the large central bronchi or vessels
- b) peribronchovascular lesions with prominent internal CT air-bronchograms, which
were considered difficult to be avoided by needle pass
- c) lesions in patient with severe respiratory compromise
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Prospective
Outcome Measure:
Success rates for mutation analysis
Outcome Time Frame:
one year
Safety Issue:
No
Principal Investigator
Ho Yun Lee, Dr.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Samsung Medical Center
Authority:
South Korea: Institutional Review Board
Study ID:
2011-10-078
NCT ID:
NCT01482572
Start Date:
January 2012
Completion Date:
December 2014
Related Keywords:
- Lung Cancer
- biopsy
- needle aspiration
- mutational analysis
- Carcinoma, Non-Small-Cell Lung
- Lung Neoplasms