Inclusion Criteria:

- Patients with brain metastases from a biopsy-proven primary extra-cranial tumor site,
excluding lymphoma, germ cell, and small cell lung carcinoma histologies.

- One to four metastases, and all lesions < 3.5 cm in maximal diameter. Extracranial
metastases is of minimal volume or stable with treatment. - Karnofsky performance
status ≥ 70

Exclusion Criteria:

- None of the lesions is abutting or within critical neurological structures:
*brainstem

- optic chiasm

- eye, and optic nerve.

- The clearance between metastatic lesions and all critical structures must be at least
2 mm.

- Patients must not have leptomeningeal disease.

- Contraindications to imaging or radiation (e.g. pregnancy, elevated serum creatinine,
allergy to contrast agents, severe claustrophobia, metal particles in the eye).