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Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome


N/A
N/A
N/A
Not Enrolling
Female
Polycystic Ovary Syndrome

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Trial Information

Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome


Poly cystic ovarian syndrome (PCOS) is a common hormonal disorder in women that affecting of
6.6-6.8% of women o f reproductive age. PCOS associated with a broad range of clinical,
hormonal and metabolic disorders consist of hirsutism, Obesity, Acne and elevated male
hormones, anovulatory cycles, dyslipidemia and infertility.

Metformin is an oral hyperglycemic agent witch by decrease insulin resistance and improving
serum glucose level in diabetic patients and anovulatory cyle in women with PCOS. The goal
of this study is to evaluate the efficacy of different dosage of metformin on menstruation
and lipid profile in women with PCOS in banda-abbas.


Inclusion Criteria:



- Women with PCOS

Exclusion Criteria:

- avoiding to participate in the study

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Lipid profile

Outcome Description:

The serum levels of Cholesterol, LDL, HDL and Triglyceride were measured before and after of treatment in both groups.

Outcome Time Frame:

6 month

Safety Issue:

No

Principal Investigator

Nazanin Abdi, resident

Investigator Role:

Principal Investigator

Investigator Affiliation:

Hormozgan University of Medical Sciences (HUMS)

Authority:

Iran: Ministry of Health

Study ID:

Metformin in PCOS

NCT ID:

NCT01474967

Start Date:

February 2010

Completion Date:

February 2011

Related Keywords:

  • Polycystic Ovary Syndrome
  • polycystic ovary syndrome
  • lipid profile
  • metformin
  • Polycystic Ovary Syndrome

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