Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome
Poly cystic ovarian syndrome (PCOS) is a common hormonal disorder in women that affecting of
6.6-6.8% of women o f reproductive age. PCOS associated with a broad range of clinical,
hormonal and metabolic disorders consist of hirsutism, Obesity, Acne and elevated male
hormones, anovulatory cycles, dyslipidemia and infertility.
Metformin is an oral hyperglycemic agent witch by decrease insulin resistance and improving
serum glucose level in diabetic patients and anovulatory cyle in women with PCOS. The goal
of this study is to evaluate the efficacy of different dosage of metformin on menstruation
and lipid profile in women with PCOS in banda-abbas.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
The serum levels of Cholesterol, LDL, HDL and Triglyceride were measured before and after of treatment in both groups.
Nazanin Abdi, resident
Hormozgan University of Medical Sciences (HUMS)
Iran: Ministry of Health
Metformin in PCOS