Trial Information

High Curability Via Intensive Reinduction Chemotherapy and Stem Cell Transplantation in Young Adults With Relapsed Acute Lymphoblastic Leukemia in Sweden 2003-2007

This is a national, multicenter, prospective, population-based study of outcome among adult
patients aged 19 to 65 years with ALL relapse diagnosed during 2003-2007 in Sweden. Most of
the patients had primary treatment according to National guidelines for ALL as recommended
by The Swedish Adult ALL Group (SVALL). The guidelines suggest two different treatment
protocols for early relapses, and retreatment according to the initial therapy for late
relapses, with the intention to proceed to allogeneic SCT in CR2 for eligible patients. The
aim of the current study was to assess outcome among adult patients after first ALL relapse,
and the utilization and efficacy of recommended protocols and of allogeneic SCT in this
setting.