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Copeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water Homeostasis


N/A
15 Years
N/A
Open (Enrolling)
Both
Pituitary Adenoma

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Trial Information

Copeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water Homeostasis


Inclusion Criteria:



- All consecutive patients who undergo surgery for an intra- or suprasellar lesion,
either by craniotomy or by transphenoidal resection.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

diagnostic accuracy, i.e. difference of copeptin levels between patients without and patients with postoperative DI, of copeptin in the diagnosis of water disturbance in neurosurgical patients

Outcome Description:

daily blood sampling will allow to diagnose DI or SIADH during hospital stay. Copeptin levels will be compared between patients with uncomplicated postoperative course and patients with development of DI or SIADH.

Outcome Time Frame:

daily during hospital stay of the patient, on average 1 week

Safety Issue:

No

Authority:

Switzerland: Ethikkommission

Study ID:

COOP Study

NCT ID:

NCT01465672

Start Date:

October 2011

Completion Date:

December 2013

Related Keywords:

  • Pituitary Adenoma
  • copeptin
  • SIADH
  • Diabetes insipidus
  • transphenoidal pituitary adenoma resection
  • pituitary adenoma
  • tumors close to pituitary gland
  • tumors close to hypothalamus
  • Adenoma
  • Pituitary Neoplasms

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