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High Plasma Level of Long Pentraxin 3 is Associated With Insulin Resistance in Women With Polycystic Ovary Syndrome


N/A
18 Years
40 Years
Not Enrolling
Female
PCOS

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Trial Information

High Plasma Level of Long Pentraxin 3 is Associated With Insulin Resistance in Women With Polycystic Ovary Syndrome


Inclusion Criteria:



- Absence of significant abnormalities on physical examination except hirsutism

- No lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy

- Normal thyroid function and prolactin level

- Absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic
disease

Exclusion Criteria:

- Pregnant

- Possible ovarian tumors,

- Congenital adrenal hyperplasia or

- BMI greater than 35 kg/m2

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Cross-Sectional

Outcome Measure:

Level of of pentraxin3 in cases with Polycystic Ovarian Syndrome

Outcome Description:

Mean PTX3 was significantly higher in patients with PCOS. This means that there is increased level of inflamation in patients with PCOS.

Outcome Time Frame:

1 year

Safety Issue:

Yes

Principal Investigator

Aydogan Aydogdu, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Gulhane School of Medicine Dep. of Endocrinology and Metabolism

Authority:

Turkey: Ethics Committee

Study ID:

23.10.2011

NCT ID:

NCT01463969

Start Date:

May 2010

Completion Date:

May 2011

Related Keywords:

  • PCOS
  • PCOS and PTX3 levels
  • Insulin Resistance
  • Polycystic Ovary Syndrome

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