A Prospective, Dual-center, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy of abobotulinumtoxinA (BTX-A) in Improving Forehead Wounds After Mohs Micrographic Surgery and Reconstruction for Skin Cancer
- Outcomes by the Patient and Observer Assessment Scale (POSAS), Visual Analog Scale, and
Patient Satisfaction Survey.
- Study consists of 5 clinic visits over approximately 6 months
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Patient and Observer Assessment Scale (POSAS)
The Patient and Observer Scar Assessment Scale (POSAS) consists of two numeric scales. One scale is completed by the patients, the other by the clinician. This scale is different than previous scales because it takes the patient's input into consideration. It has good internal consistency and interobserver reliability. The assessment will take place at Day 0, Week 1, Week 6, and Month 6.
Margaret Mann, MD
University Hospitals of Cleveland
United States: Institutional Review Board
Mann-Cohen Version 2
|AboutSkin Dermatology and DermSurgery||Englewood, Colorado 80113|
|University of California, Irvine: Department of Dermatology||Cleveland, Ohio 44106|