Inclusion Criteria

Inclusion criteria:

- in order to be eligible for the study, the diagnosis of gastric cancer and/or lower
esophageal cancer must be confirmed histologically. CNS involvement must be confirmed
either via independent neuroradiological and/or positive CSF cytology.

Exclusion criteria:

- Patients whose diagnosis is not confirmed upon pathological review or where the CNS
involvement cannot be confirmed after neuroradiological review will be excluded from
this study.