Inclusion Criteria:

To be eligible for an unlicensed umbilical cord blood (UCB) unit, the subject must meet
each of the eligibility criteria listed below:

- Subjects with any diagnosis for which there is an institutional review board (IRB)
approved treatment protocol that requires UCB as a source of hematopoietic stem cells
for lympho‐hematopoietic reconstitution after myeloablative or non myeloablative
conditioning.

- Subject (or parent/guardian) must provide written informed consent for the use of
unlicensed UCB units with co‐enrollment onto a University of Minnesota IRB‐approved
clinical trial that details the disease specific treatment plan that prescribes the
use of UCB as source of cells

- Subject has an unlicensed UCB unit that meets required cell dose and HLA matching
criteria (as defined in the primary treatment protocol) that is considered negative
for tested blood‐borne pathogens and also lack an 'equivalent', licensed UCB unit
from a University of Minnesota approved Cord Blood Bank

Exclusion Criteria:

- Exclusion criteria are specified in the treatment protocol according to indication.