Feasibility Study: FES-PET to Determine ER-expression in Epithelial Ovarian Cancer
Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Diagnostic
The feasibility of FES-PET to visualize and quantify ER-positive lesions in epithelial ovarian cancer.
Ovarian cancer patients planned for surgery or in which histology/cytology will be obtained, will undergo FES-PET/CT. FES-PET/CT will be qualitatively analyzed to determine whether ovarian cancer lesions can be visualized. FES-uptake will be quantified for all known lesions. Patient material will be stained for ER-expression to determine whether ER-positive metastases show FES-uptake.
approximately 1 month
Geke AP Hospers, MD, PhD
University Medical Centre Groningen
Netherlands: Medical Ethics Review Committee (METC)