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Does an Acute Bout of Exercise Affect Smoking Topography?

18 Years
65 Years
Open (Enrolling)

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Trial Information

Does an Acute Bout of Exercise Affect Smoking Topography?

Lung cancer is the leading cause of cancer death in Canadians (Canadian Cancer Society, in
which cigarette smoking is responsible for 85% of these cases. Smoking topography, a key
facet of smoking behaviour, can be subjectively or objectively measured by quantifying puff
volume, maximum puff velocity, interpuff interval, puff duration, number of puffs per
cigarette, and the time to smoke a single cigarette. Smoking topography can estimate
exposure to carcinogenic toxins present in cigarette smoking (Djordjevic, Hoffman, &
Hoffman, 1997). Evidence exists to support that exercise modifies smoking topography
(Katomeri & Taylor 2006; Mikhail, 1983; Reeser, 1983; Zacny & Stitzer, 1985).

Recently, Faulkner and colleagues (2011; N = 18) were the first to implement a handheld
smoking topography device (CReSS Pocket) to measure smoking behaviour in the context of an
acute bout of exercise after a temporary period of abstinence. They found that brisk walking
influences an individual's smoking topography. In specific, participants assigned to the
exercise condition smoked less per puff and took shorter puff durations, compared to the
passive sitting condition. Overall, smoking topographical studies require further
investigation due to methodological flaws in order to allow for the objective collection of
smoking behaviour data and improved external validity in a sufficiently powered study.
Furthermore, the role of cravings, withdrawal and affect as potential mediators of
topographical changes due to exercise is a novel area of research.

Inclusion Criteria:

- 18 to 64 years of age

- Smoke 10 cigarettes or more per day

- Not have any medical condition that is contraindicative for exercise

- Not be pregnant or intending on being pregnant over the course of the study

- Be able to read and write in English

- Have a telephone or an email account so that they can be contacted

- Completed the Physical Activity Readiness Questionnaire (PAR-Q)

- Have Medical Doctor's clearance if they answer "YES" to one or more questions on the
Physical Activity Readiness Questionnaire (PAR-Q)

- Have not been engaged in a serious quit attempt in the last six months

- Have been smoking for more than 2 years

- Must not be suffering from an illness (e.g. cold) that would affect their typical
smoking behaviour

Exclusion Criteria:

- Contraindication to exercise (e.g., disability, unstable angina)

- On medication for physical and/or mental health reasons that would make compliance
with the study protocol difficult or dangerous

- Have substance dependency problems (e.g., alcohol)

- Are pregnant

- Be younger than 18 years of age

- Be 64 years or older prior to completion of the study

- Have been engaged in a serious quit attempt in the last six months

- Have been smoking for less than 2 years

- Suffering from an illness (e.g. cold) that would affect their typical smoking

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Outcome Measure:

Smoking topography

Outcome Description:

Smoking topography will be assessed using the Clinical Research Support System (CReSS) Pocket, a computer-based, battery-powered, hand-held unit by Plowshare Technologies®. The CReSS Pocket has an orifice flow meter mouthpiece, and a pressure drop related to the flow rate that is produced when a puff is taken. From the flow rate, the CReSS derives puff count (number of puffs per cigarette), puff volume (the volume of carbon monoxide take in during each puff), puff duration (length of time for each puff), inter-puff interval (amount of time between puffs), and time to first puff.

Outcome Time Frame:

One week

Safety Issue:


Principal Investigator

Harry Prapavessis, Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Western Ontario, Canada


Canada: Ethics Review Committee

Study ID:




Start Date:

August 2011

Completion Date:

August 2012

Related Keywords:

  • Cancer
  • exercise
  • topography
  • cravings
  • smoking behaviour
  • Smoking