Optimization of fMRI for the Study of Basal Ganglia Activation in Parkinson's Disease: T2* Measurement in the Cortex and the Basal Ganglia
80 subjects (40 PD patients and 40 paired healthy volunteers (on sex and age)) aged 40-80
years will be included. PD patients will be recruited in the Department of Neurology of CHU
of Clermont-Ferrand. Healthy volunteers will be selected in clinical trial database. This
study will consist of one visit (at J0) during which subjects will undergo a MRI (a single
acquisition of 40 minutes approximately). PD patients will be further questioned on their
disease and will benefit from a neurological examination
Interventional
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
The quantitative measurement of T2* in the cortex and basal ganglia using MRI, made à J0.
at day 1
Yes
Miguel ULLA
Principal Investigator
University Hospital, Clermont-Ferrand
France: Ministry of Health
CHU-0097
NCT01429909
February 2011
February 2012
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