Know Cancer

or
forgot password

Pilot Project of Adaptive Thoracic Radiotherapy for Small Cell Lung Cancer


Phase 1
18 Years
N/A
Open (Enrolling)
Both
Small Cell Lung Cancer

Thank you

Trial Information

Pilot Project of Adaptive Thoracic Radiotherapy for Small Cell Lung Cancer


Inclusion Criteria:



- patients with histologically or cytologically proven newly diagnosed small cell lung
cancer

- chest-confined disease (including bulky intrathoracic disease)

- adequate pulmonary function tests (FEV-1>1.0 L, DLCO>50%)

- patients of childbearing potential must practice adequate contraception

- Age > or = 18 years

- Karnofsky performance status > or = 70

- eligible for concurrent chemoradiotherapy

Exclusion Criteria:

- patients who have undergone complete or subtotal tumour resection

- evidence of non-small cell histology

- prior or concurrent malignancy except non-melanomatous skin cancer unless
disease-free for at least 5 years

- prior RT to the thorax or neck

- compromised lung function with inadequate pulmonary function tests
(FEV-1<1.0,DLCO<50%)

- pregnant women

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Differences in normal structure/target volume doses achievable using adaptive radiotherapy approach

Outcome Description:

Differences in normal structure/target volume doses achievable using adaptive radiotherapy approach will be measured in centigray

Outcome Time Frame:

12-24 months

Safety Issue:

No

Authority:

Canada: Health Canada

Study ID:

CCI Yee 25708

NCT ID:

NCT01426841

Start Date:

August 2011

Completion Date:

January 2013

Related Keywords:

  • Small Cell Lung Cancer
  • Small cell lung cancer
  • Adaptive radiotherapy
  • Thoracic radiotherapy
  • Lung Neoplasms
  • Small Cell Lung Carcinoma

Name

Location