A Novel Approach to Endometrial Preparation in Recipients of Donor Cycles
Currently a combination of medications is used to prepare the uterine lining of recipients
for implantation in egg donor cycles. The protocol used most commonly is as follows:
Initially the individual's own pituitary-ovarian system is suppressed using a GnRH agonist
so there are not conflicting signals sent to the uterus. This is followed by hormonal
medication identical to what is secreted by the ovaries to prepare the uterine lining for
subsequent embryo transfer in donor egg cycles.This preparation typically takes a minimum of
four weeks.
This study will compare a different medication, a GnRh antagonist (which is commonly used in
IVF) to suppress an individual's system during the preparation of the uterine lining. This
protocol would generally take only two weeks to prepare the uterine lining.
Interventional
Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
endometrial thickness measured by ultrasound
In office ultrasound to measure thickness of endometrial lining.
2-4 weeks
No
Maureen Kelly, MD
Principal Investigator
Society Hill Reproductive Medicine
United States: Institutional Review Board
39604
NCT01424618
January 2006
Name | Location |
---|---|
Society Hill Reproductive Medicine | Philadelphia, Pennsylvania 19107 |