Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia
Patients with high risk or relapsed acute lymphoblastic leukaemia (ALL) have a worse
prognosis compared to all other patients with ALL. For these patients additional therapy
approaches are required after they have achieved remission with multimodal chemotherapy.
Allogeneic haematopoetic stem cell transplantation shows promising results mainly due to an
immunological antileukaemic control by the graft-versus-leukaemia effect but treatment
related mortality and morbidity remains a serious problem.
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Event free survival
Event-free and overall survival after allogeneic HSCT
Christina Peters Peters, Prof MD PHD
St. Anna Kinderkrebsforschung
Austria: Federal Office for Safety in Health Care