Circulating Tumor Cells in Patients Undergoing Stereotactic Body Radiotherapy for Low- and Intermediate-Risk Prostate Cancer
SBRT (stereotactic body radiotherapy) may decrease or actually increase CTC levels in
patients with cancer, and knowledge about the effects of different therapies, including
SBRT, on CTC levels will be of general interest to the oncology community. Patients will
undergo blood draws at defined times as indicated below.
1. Prior to CT-simulation, but more than 2 days after digital rectal examination
2. Within 24 hours following CT simulation (an endorectal balloon is used at the time of
3. Within 24 hours following the first treatment
4. Within 24 hours following the third treatment
5. Within 1 week following the fifth treatment
Observational Model: Case-Only, Time Perspective: Prospective
To review the level of changes in circulating tumor cells with radiation.
The investigator will review the coutns of circulating tumor cells (CTC). If there are significant changes in CTC levels with radiation, future studies will determine the prognostic significance of this information.
Jeffrey Meyer, MD
University of Texas Southwestern Medical Center
United States: Institutional Review Board
|University of Texas Southwestern Medical Center||Dallas, Texas|