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Prognostic Potential of Cell Surface Markers and Pim Kinases in Multiple Myeloma


N/A
18 Years
N/A
Open (Enrolling)
Both
Multiple Myeloma

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Trial Information

Prognostic Potential of Cell Surface Markers and Pim Kinases in Multiple Myeloma


Inclusion Criteria:



- A diagnosis of multiple myeloma or possible multiple myeloma who will have a bone
marrow biopsy and aspirate

- Planned therapy with standard chemotreatment for multiple myeloma

- Laboratory data such as calcium, beta 2-microglobulin, albumin, creatinine and bone
survey available for staging purpose.

- ≥18 years old

Exclusion Criteria:

- < 18 years old

- Patients who will not receive chemotreatment

- Patients whose treatment records are not available

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Measure the expression levels of CXCR4, CD47, and pS6 by flow cytometry in myeloma patient's marrow aspirate

Outcome Description:

Our Aim 1 is to perform a corrective study to measure the expression levels of CXCR4, CD47, and pS6 by flow cytometry in myeloma patient's marrow aspirate and correlate their expression level with patients' treatment responses

Outcome Time Frame:

3 years

Safety Issue:

No

Authority:

United States: Institutional Review Board

Study ID:

101565

NCT ID:

NCT01410981

Start Date:

July 2011

Completion Date:

Related Keywords:

  • Multiple Myeloma
  • Multiple Myeloma
  • Neoplasms, Plasma Cell

Name

Location

Medical University of South CarolinaCharleston, South Carolina  29425-0721