Know Cancer

or
forgot password

Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.


N/A
18 Years
N/A
Not Enrolling
Both
Carcinoma, Carcinoma, Renal Cell, Neuroendocrine Tumors, Carcinoid Tumor, Pancreatic Islet Cell Tumors

Thank you

Trial Information

Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.


- To analyse the concentration catecholamines in thrombocytes of patients with clear cell
renal cell carcinoma and low grade neuroendocrine tumours.

- To compare these concentrations with the concentrations catecholamines in thrombocytes
of healthy controls.

- To analyse the concentration catecholamines in thrombocytes of patients with clear cell
renal cell carcinoma and patients with low grade neuroendocrine tumours with and
without medication.


Inclusion Criteria:



- Age 18 years old or older.

- Patients with clear cell renal cell carcinoma with metastases or patients with a
low-grade neuro-endocrine tumor with metastases.

- Written informed consent

Exclusion Criteria:

- Use of L-dopa or SSRI.

- Patients with a second primary malignancy.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Cross-Sectional

Outcome Measure:

Difference in concentrations DA and 5-HT in thrombocytes of patients with clear cell renal cell carcinoma and healthy controls, and patients with low grade neuroendocrine tumours and healthy controls.

Outcome Time Frame:

one year

Safety Issue:

No

Principal Investigator

Sjoukje F. Oosting, MD

Investigator Role:

Study Chair

Investigator Affiliation:

University Medical Centre Groningen

Authority:

The Netherlands: Medical Ethics Review Committee (METC)

Study ID:

230520112

NCT ID:

NCT01398306

Start Date:

July 2011

Completion Date:

April 2012

Related Keywords:

  • Carcinoma
  • Carcinoma, Renal Cell
  • Neuroendocrine Tumors
  • Carcinoid Tumor
  • Pancreatic Islet Cell Tumors
  • Angiogenesis Inhibitors
  • Neoplasms, Glandular and Epithelial
  • Neoplasms by Histologic Type
  • Neoplasms
  • Adenocarcinoma
  • Kidney Neoplasms
  • Urologic Neoplasms
  • Urogenital Neoplasms
  • Neoplasms by Site
  • Kidney Diseases
  • Angiogenesis Inducing Agents
  • Biological Markers
  • Carcinoid Tumor
  • Carcinoma
  • Carcinoma, Renal Cell
  • Endocrine Gland Neoplasms
  • Neuroendocrine Tumors
  • Adenoma, Islet Cell

Name

Location