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Strength Training on Pancreatic Cancer

Not Enrolling
Pancreatic Neoplasms, Cachexia, Myopathy

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Trial Information

Strength Training on Pancreatic Cancer

Sudden out-of-hospital cardiac arrest (OOH-CA) remains a significant cause of death, in
spite of recent declines in overall mortality from cardiovascular disease. Existing methods
of emergency resuscitation are inadequate due to time delays inherent in the transport of a
trained responder with defibrillation capabilities to the side of the OOH-CA victim.
Existing Emergency Medical Services (EMS) systems typically combine paramedic Emergency
Medical Technician (EMT) services with some level of community involvement, such as
bystander cardiopulmonary resuscitation (CPR) training. Some communities include automated
external defibrillators (AEDs) at isolated sites or in mobile police or fire vehicles. A
comprehensive, integrated community approach to treatment with AEDs would have community
units served by these volunteer non-medical responders who can quickly identify and treat a
patient with OOH-CA. Such an approach is termed Public Access Defibrillation (PAD).

Inclusion Criteria:

- patients with pancreatic carcinomas after surgery (resection or exploration)

- given consent

Exclusion Criteria:

- acute infection

- pain

- no mobility or ability for walking or standing

- severe neurological disorders (apoplex, morbus Parkinson, paresis of the lower

- severe cardiac or cardiovascular diseases (z.B. heart insufficiency NYHA III,
myocardial infarction <3 months)

- rhytmical disorders, that contraindicate ergospirometric examinations

- cardiac therapy with digitalis pharmacy

- unclear syncopes

- severe pulmonal insufficiency

- renal insufficiency (GFR < 30% at Krea >3 mg/dl)

- synchronous participation in an other clinical trial

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

muscle mass and strength

Outcome Time Frame:

after 8 weeks of intervention

Safety Issue:


Principal Investigator

Jens Werner, Prof. Dr. med.

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Heidelberg


Germany: Ethics Commission

Study ID:




Start Date:

January 2009

Completion Date:

December 2011

Related Keywords:

  • Pancreatic Neoplasms
  • Cachexia
  • Myopathy
  • Cachexia
  • Neoplasms
  • Muscular Diseases
  • Pancreatic Neoplasms