Know Cancer

or
forgot password

Developing Individualized Strategies to Prevent Nausea and Vomiting


N/A
21 Years
70 Years
Not Enrolling
Both
Postoperative Nausea and Vomiting, Genetic Polymorphisms

Thank you

Trial Information

Developing Individualized Strategies to Prevent Nausea and Vomiting


Inclusion Criteria:



- adult (i.e. at least 21 years of age) ambulatory surgery patients, with a duration of
1-4 hours

- able to understand, read, and write in English, are ASA physical status 1-3, and are
high risk PDNV patients (with 3 or more of the following risk factors:

- female gender

- age < 50

- history of PONV and/or currently prone to motion sickness, and expectation of post-op
opioid use).

Exclusion Criteria:

- patients not at high risk for PDNV (as described above)

- patients <21 years of age

- planned inpatient surgical patients

- planned total intravenous anesthesia, sedation, or regional technique without inhaled
anesthetic

- inability to provide informed consent in English

- pregnant or breastfeeding

- persistent and/or current nausea/vomiting.

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Outcome Measure:

Incidence of post-discharge nausea and vomiting (PDNV)

Outcome Time Frame:

48 hours post-discharge

Safety Issue:

No

Authority:

United States: Institutional Review Board

Study ID:

1R01CA163074-01A1

NCT ID:

NCT01393288

Start Date:

April 2012

Completion Date:

November 2015

Related Keywords:

  • Postoperative Nausea and Vomiting
  • Genetic Polymorphisms
  • Nausea
  • Vomiting
  • Postoperative Nausea and Vomiting

Name

Location

University of Kansas Medical CenterKansas City, Kansas  66160-7353
University of California, San FranciscoSan Francisco, California  94143
Cleveland ClinicCleveland, Ohio  44195
Ohio State University Medical CenterColumbus, Ohio  43210
Brigham & Women's HospitalBoston, Massachusetts  02115
University of Kentucky HospitalLexington, Kentucky  40536