Microbubble Contrast Ultrasound and Transient Elastography Imaging of Early Breast Cancer
Women who have imaging findings suggestive of DCIS, who are having breast ultrasound and who
are candidates for surgery will be eligible. They will receive a contrast-enhanced breast
ultrasound after the intravenous injection of a microbubble contrast agent which will show
the microvascularity. A subset of women will also have ultrasound elastography performed of
the abnormality to evaluate its stiffness.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Evidence of the presence of angiogenic tumour vasculature in patients diagnosed with DCIS utilizing contrast enhanced ultrasound.
The participant will be followed up till the results of the biopsy, an expected average of 3 months.
Roberta A Jong, FRCPC
Sunnybrook Health Sciences Centre
Canada: Health Canada