Trial Information
DNA Double-strand Breaks Following Myocardial Scintigraphy
Inclusion Criteria:
- myocardial SPECT clinically indicated
Exclusion Criteria:
- acute leukaemia or lymphoma
- radiation or chemotherapy in the last 6 months
- x-ray or scintigraphy within the last 3 days
- age below 18 years
- eGFR of below 60 ml/min
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Radiation-induced DNA double-strand breaks after myocardial scintigraphy.
Outcome Description:
DNA double-strand breaks will be measured before and up to 48 hours after radiation.
Outcome Time Frame:
48 hours
Safety Issue:
Yes
Principal Investigator
Marc Dewey
Investigator Role:
Principal Investigator
Investigator Affiliation:
Charité Berlin
Authority:
Germany: Ethics Commission
Study ID:
EA4/004/11
NCT ID:
NCT01380821
Start Date:
March 2011
Completion Date:
January 2013
Related Keywords:
- Coronary Artery Disease
- clinical indication for myocardial SPECT
- suspected or known coronary artery disease
- Coronary Artery Disease
- Myocardial Ischemia
- Coronary Disease