Inclusion Criteria:

- Patients who are clinically diagnosed as having stage Ta, T1, histological grade G1,
G2 urothelial carcinoma of the bladder

- Patients who are confirmed to be urinary cytology negative (class I, class II) within
4 weeks prior to the present TURBT.

- P.S : 0-2 according to the ECOG.

Exclusion Criteria:

- Patients with a primary and solitary tumor.

- CIS lesions in the bladder or a history thereof.

- Grade 3 disease or a history thereof.

- Patients experiencing recurrence within 3 months following TURBT for prior NMIBC.

- Patients having stage T1 and high-grade disease.

- Invasive cancer of T2 or greater, with definite lymph node or other organ metastasis,
or a history thereof.

- Patients who received intravesical chemotherapy/immunotherapy treatment within 6
months prior to the present TURBT.

- Patients who underwent systemic chemotherapy or radiotherapy whose field of exposure
included the bladder.

- Patients with suspected bladder perforation at the time of the present TURBT.

- A complication of a malignant tumor of the upper urinary tract or urethra, or a
history thereof.

- Malignancy within 5 years other than NMIBC (except thyroid cancer)

- A serious viral or bacterial infection within the last 4 weeks.