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Surgical Procedures for Advanced Tumor Disease. A Prospective Study Evaluating Quality of Life

18 Years
Open (Enrolling)
Advanced Cancer

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Trial Information

Surgical Procedures for Advanced Tumor Disease. A Prospective Study Evaluating Quality of Life

What is the impact on quality of life by operations in symptomatic advanced tumor disease ?
After informed consent patients in known palliative situations and with localized symptoms
due to tumor growth will be enrolled in our study. The investigators will assess Quality of
life with the EORTC QLQ C30-questionnaire and collect data about the disease an the actual
state of the patients.

By the time of discharge out of hospital the investigators will hand out the questionnaire
again and the investigators will collect data regarding the therapies, operations,
complications, reinterventions, time spent on a intensive care unit, time spent in hospital.

The questionnaire will be completed after 4 and 12 weeks as well.

Inclusion Criteria:

- informed consent

- tumor patients within a known palliative situation, patients do know about the
absence of a curative treatment

- patients are symptomatic because of localized tumor growth

- patients having an operation for symptom relief or treated without surgery

Exclusion Criteria:

- patients with an only intraoperatively seen palliative tumor disease

- debulking operations, prophylactic operations for prevention of symptoms, operations
for venous access (an exception will be made for enteric bypass operations in
patients with a yet preserved passage)

- dementia, age ≤ 18, barrier of speech

Type of Study:


Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Quality of life 4 weeks after palliative surgery

Outcome Description:

Quality of life will be measured by the questionnaire EORTC-QLQ-C30 (European Organization for Research and Treatment of Cancer-Quality of Life).

Outcome Time Frame:

4 weeks after palliative surgery

Safety Issue:


Principal Investigator

Carsten T. Viehl, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Surgery, University Hospital of Basel


Switzerland: Ethikkommission

Study ID:

EK 10/10



Start Date:

July 2010

Completion Date:

September 2012

Related Keywords:

  • Advanced Cancer
  • palliation
  • quality of life
  • surgery
  • surgery; palliative
  • lifestyle
  • Neoplasms