Expression of T Immunoregulatory Proteins in ALK+ Anaplastic Large Cell Lymphoma (ALCL)
OBJECTIVES:
- To determine the expression of immunoregulatory proteins including CD4, FOXP3 and CD276
in anaplastic large cell lymphoma (ALCL).
- To correlate the expression of these proteins with the levels of anaplastic lymphoma
kinase (ALK) autoantibodies in patient of ANHL0131.
OUTLINE: Archived tissue microarray samples are analyzed by mass spectrometry and validated
by Western blotting, flow cytometry, and IHC.
Observational
N/A
Expression of immunoregulatory proteins including CD4, FOXP3 and CD276 in ALCL
No
Megan S. Lim, MD, PhD
Principal Investigator
C.S. Mott Children's Hospital at University of Michigan Medical Center
United States: Federal Government
CDR0000701026
NCT01366170
May 2011
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