Expression Levels of RNA-induced Silencing Complex (RISC) Components TARBP1, TARBP2, Argonaute-1, Argonaute-2, PACT and Microprocessor Complex Component DGCR8 in Epithelial Skin Cancer
Patients with premalignant actinic keratoses, basal cell carcinomas and squamous cell
carcinomas were included in the study. Punch biopsies were harvested from the center of the
tumors, from sites of healthy skin and a healthy control group. DGCR8, TARBP1, TARBP2,
argonaute-1, argonaute-2 and PACT mRNA expression levels were detected by quantitative
real-time reverse transcriptase polymerase chain reaction.
Observational Model: Case-Only, Time Perspective: Retrospective
Falk G Bechara, PD Dr.
Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum
Germany: Ethics Commission