A Two-arm Phase II Randomized Study, Comparing Adaptive Biological Imaging - Voxel Intensity - Based Radiotherapy (Adaptive Dose Escalation) Versus Standard Radiotherapy for Head and Neck Cancer.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
To obtain 25 % increase in local control at 1 year with adaptive dose escalation comparing to standard treatment.
18F-FDG-PET/CT scans will be performed.
at 1 year
Wilfried De Neve, Ph.D., M.D.
University Hospital, Ghent
Belgium: Ethics Committee