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The ARTERY FIRST Approach for Resection of Pancreatic Head Cancer

Phase 3
18 Years
Open (Enrolling)
Pancreatic Head Cancer

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Trial Information

The ARTERY FIRST Approach for Resection of Pancreatic Head Cancer

This is a prospective non-randomized trial with two study groups. The trial is designed to
show if the ARTERY FIRST approach reduces the rate of R1 resections in patients undergoing
surgery for cancer of the pancreatic head.

After the diagnosis of cancer of the pancreatic head by clinical, laboratory and imaging
evaluation patients who are scheduled for resection will be screened for inclusion into the
trial. Informed consent is obtained at least on the day before surgery and patients meeting
the eligibility criteria will be enrolled into the study.

Inclusion Criteria:

- Pancreatic head cancer (diagnosis by clinical, laboratory and radiological

- Patients scheduled for curative resection

- No evidence of distant metastases

- Age equal or greater than 18 years

- Informed consent

Exclusion Criteria:

- Expected lack of compliance

- Impaired mental state or language problems

- patient having had neoadjuvant radiochemotherapy

Type of Study:


Study Design:

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Rate of R1 resections

Outcome Description:

positive resection margins as described by the pathologists of the University of Heidelberg

Outcome Time Frame:

up to 1.5 years

Safety Issue:



Germany: General, Visceral and Transplantation Surgery, University hospidal Heidelberg

Study ID:




Start Date:

March 2010

Completion Date:

July 2011

Related Keywords:

  • Pancreatic Head Cancer
  • Head and Neck Neoplasms