Inclusion Criteria:

- Must be male or female and at least 18 years of age

- Female patients must be of: non-childbearing potential or if of childbearing
potential then have a negative serum and urine pregnancy test and using effective
contraception

- Ability to provide informed consent

- primary diagnosed and histologically confirmed sBCC located on the trunk or
extremities which is suitable for excision

Exclusion Criteria:

- location of the sBCC lesion within 10cm of an incompletely healed wound, on the hand
or foot, on the breast of women, on the anogenital area.

- Undergone cosmetic or therapeutic procedures within 2cm of the selected treatment
area in the 2 weeks prior to the screening visit.

- Use of acid-containing therapeutic products within 2 cm of the selected treatment
area in the 2 weeks prior to the screening visit

- Use of topical moisturisers/creams/lotions (non-medicated/non-irritant salves are
acceptable), artificial tanners or topical steroids: within 2 cm of the selected
treatment area.

- Have received treatment with immunomodulators, or interferon/interferon inducers,
systematic medications that suppress the immune system or UVB in the last 4 weeks

- Have undergone treatment with 5-FU, imiquimod, diclofenac or photodynamic therapy
within 2 cm of the selected treatment area within 8 weeks prior to any screening
visit.

- Use of systemic retinoids.

- Those who are currently participating in any other clinical trial

- Those known or suspected of not being able to comply with the requirements of the
protocol

- Females who are pregnant or are breastfeeding