Trial Information

Retrospective Study of APR Results Regarding Patients' Self Reported Quality of Life

Low rectal cancer treated by abdominoperineal resection (APR, rectal amputation)has worse
prognosis than other rectal cancers, both regarding local recurrence and cancer specific
survival. With a view to improve local recurrence rates a more extensive perineal operation
(excision of the levator muscle) has been suggested. In our university hospital thie
technique was introduced for all surgeons January 2007. A population of all patients
operated from 1 January 2007 to 31 December 2009 was compared to all patients operated from
1 January 2004 to 31 December 2006 using the traditional, less extensive method, in all a
six year period and 158 patients.

A specific questionnaire was developed after in depth interviews, and was face-validated by
patients who had undergone an APR. This questionnaire will be sent out to all patients in
our population who are still alive.

The patients will be contacted first by a letter of invitation, later called by telephone to
be given more information and asked for permission to send the questionnaire.

The send out of invitation letters will start March 2011.