Study of Human Papillomavirus Related Genital Pathology Among HIV Positive
Data were be collected into evaluate:
- Analysis of prognostic factors (CD4, antiviral therapy) of cervical lesions, using Cox
- Estimation of rates of Incidence of high grade lesions, of recurrence after surgical
treatments using Kaplan Meier tests.
- Logistic regression analysis for the study of factors associated with complete excision
after surgical treatment.
- SIR (standardised incidence rate) evaluation for cervical cancer
Study procedures are Annual follow-up in case of normal Pap smear, biannual follow-up in
case of cervical lesions. Surgical management of High grade lesions.
Observational Model: Cohort, Time Perspective: Prospective
Isabelle Heard, MD
Unité biologie de la reproduction, GH Pitié Salpétrière
France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)