Pilot Study to Determine the Utility of [18F] 3'-Deoxy-3'-Fluorothymidine- Positron Emission Tomography in Monitoring Patient Response to Chemotherapy in Neuroblastoma
The purpose of this research study is to observe the changes within the tumor cells which
may improve the understanding of how tumors grow and how they respond to various treatments.
These changes will be compared with results of the physical examination and scans (CT and
MRI) that are done as part of clinical care. Images will be made showing the distribution
throughout the body of substances containing a small amount of radioactive material. This
procedure is called a PET scan. The radioactive substances (tracer compound) in this study
are [F-18] FLT.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
To determine whether 18F-FLT-PET is a sensitive tool to image neuroblastoma.
1st PET - At diagnosis
Anthony F. Shields, M.D., Ph.D.
Karmanos Cancer Institute
United States: Institutional Review Board
|Children's Hospital of Michigan||Detroit, Michigan 48201|