Effect of Ergocalciferol Repletion on Urine Calcium Among Stone Formers With Vitamin D Deficiency and Hypercalciuria
The investigators plan to conduct a clinic-based interventional study of 30 patients
followed at outpatient urology clinics associated with New York Presbyterian Hospital
(NYPH). The intervention is supplementation with oral ergocalciferol 50,000 IU per week for
8 weeks, and each participant will serve as his/her own control. The formulation, dose, and
duration of vitamin D therapy is reflective of that which is given in routine clinical
practice to patients with vitamin D deficiency. The outcome is the change in urinary calcium
excretion.
Interventional
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Change in 24 Hour Urine Calcium
Elevated values of urine calcium are a risk factor for recurrence of calcium kidney stones
8 weeks
Yes
United States: Institutional Review Board
AAAF3346
NCT01295879
September 2010
June 2011
Name | Location |
---|---|
New York Presbyterian Hospital | New York, New York 10021 |