Natural History of HPV Infections in Mid-Adult Women
30 Years
50 Years
Female
Papillomavirus Infections
Trial Information
Natural History of HPV Infections in Mid-Adult Women
The investigators propose a longitudinal study of 500 women in order to determine rates and
risk factors for HPV infections in 30-50 year old women. Participants will be followed for
6 months and will be asked to complete online questionnaires on their health, sexual
behavior, HPV vaccinations, and cervical cancer screening. The investigators will ask
participants to self-collect monthly vaginal swab samples and self-collect 2 oral swab
samples. Women will also be asked to provide 2 blood samples. All swab samples will be
tested for type-specific HPV deoxyribonucleic acid (DNA) using a polymerase chain reaction
(PCR)-based assay, blood samples will be tested for HPV antibodies.
Inclusion Criteria:
- affiliated with the University of Washington (student, staff, faculty)
- willing to self-collect vaginal samples at home for HPV testing
- able to provide informed consent
Exclusion Criteria:
- pregnant
- have had hysterectomy
- serious medical condition which prevents completion of activities of daily living
Type of Study:
Observational
Study Design:
Time Perspective: Prospective
Outcome Measure:
Presence of type-specific HPV DNA in self-collected oral and vaginal swab samples
Outcome Time Frame:
once a month for 6 months
Safety Issue:
No
Principal Investigator
Rachel L Winer, PhD, MPH
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Washington
Authority:
United States: Institutional Review Board
Study ID:
39810-C
NCT ID:
NCT01295242
Start Date:
February 2011
Completion Date:
December 2012
Related Keywords:
- Papillomavirus Infections
- HPV
- Cervical Cancer
- Papillomavirus Infections
Name | Location |
|---|---|
| University of Washington | Seattle, Washington 98195 |
