The Effects of Radiation Therapy on the Reconstructed Breast: An Evaluation Using MR Imaging
Immediate breast reconstruction following mastectomy has become an increasingly popular and
accepted treatment option among breast cancer patients. This change in practice has
resulted in a significant number of patients who undergo radiation therapy after breast
reconstruction. Following irradiation, the reconstructed breast often experiences fibrotic
contracture, volume loss, altered pigmentation, or some combination thereof, producing an
asymmetric and aesthetically compromised result. The effects of radiation on reconstructed
breasts as well as the implications that such changes have for timing of reconstructive
surgery, post-operative management and surveillance imaging are topics of growing importance
in plastic surgery, radiology and surgical oncology.
Observational
Time Perspective: Prospective
Reconstructed Breast Volume
This will be compared at 2 points: before radiation and 1 year after radiation is completed between the 2 breasts.
up to 1 year after radiation
No
United States: Institutional Review Board
UPCC 12110
NCT01292772
December 2010
December 2013
Name | Location |
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Abramson Cancer Center of the University of Pennsylvania | Philadelphia, Pennsylvania 19104-4283 |