A Phase II Study of Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation: An Assessment of Long Term Neurocognitive, Neuroendocrine Adn Ototoxicity Outcomes
- Participants will receive proton radiotherapy at the Francis H. Burr Proton Therapy Center
which is located at the Massachusetts General Hospital. They will receive the proton
radiotherapy 5 days per week. The number of weeks the participant will be receiving proton
radiotherapy depends upon the tumor type and location and how well they are tolerating the
treatment. Participant's will have a physical exam weekly during proton radiotherapy
treatment.
Interventional
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Endocrine dysfunction
To describe the incidence of endocrine dysfunction (neuroendocrine and end organ defects) at 3 and 5 years after radiotherapy.
5 years
Yes
Torunn I. Yock, MD
Principal Investigator
Massachusetts General Hospital
United States: Institutional Review Board
10-206
NCT01288235
January 2011
Name | Location |
---|---|
Dana-Farber Cancer Institute | Boston, Massachusetts 02115 |
Massachusetts General Hospital | Boston, Massachusetts 02114-2617 |