The Use of Major Depression Inventory (MDI) in Measuring Preoperative Depressive Symptoms in Breast Cancer Patients
The Major Depression Inventory is a self-rating depression scale with 12 questions. The
questionnaire has previously been investigated in a Danish population. The scale contains
the 10 ICD-10 (International Classification of Diseases)symptoms of depression and these
symptoms are identical with the DSM-IV major depression symptoms with the exception of one
symptom, low self-esteem, which in DSM-IV (Diagnostic and Statistical Manual of Mental
Disorders) is incorporated in the symptom of guilt. On a six-point Likert scale, the
individual items measure how much of the time the symptoms have been present during the last
14 days. The MDI is then scored according to specific guidelines and can be used as both a
rating scale and a diagnostic instrument.
Patients will approximately one week after the diagnosis of breast cancer has been made,
corresponding to approximately one week before surgery, be asked to complete the MDI.
Patients therefore only complete the MDI once in the whole study. At the same time a Mini
Mental State Examination (MMSE) and questions regarding previous illnesses and medication
will be asked. Patients will not be followed up in any way.
Observational Model: Cohort, Time Perspective: Cross-Sectional
Total score on the Major Depression Inventory. When used as a diagnostic instruemtn patients witll according to the ICD-10 algorhythym be classified as mild, moderate or severe depression or no depression.
Approximately one week before surgery
Melissa V Hansen, MD
Denmark: The Danish National Committee on Biomedical Research Ethics