Inclusion Criteria:

- ≥ 50 years

- Karnofsky Index ≥ 60

- histological or by imaging proven spinal metastases (2 cm diameter as the upper
limit) inferior TH 3, which are accessible for kyphoplasty

- written informed consent obtained

- use of adequate contraceptive method by female patients of reproductive potential to
minimize risk of pregnancy

Exclusion Criteria:

- uncontrolled intercurrent medical disorder - including but not limited to ongoing or
active infection (including infections in the area of the treated spinal segment, for
example, spondylitis / osteomyelitis / skin infections) or mental illness / social
situation which affect the compliance of study requirements

- prior radiation of the same vertebra

- patients could not receive anaesthesia or surgery for medical reasons

- history of coagulation disorder associated with bleeding

- existing contraindications for MRI- or CT-scans

- pregnant or breast-feeding women