Sonographic Characterization of the Thyroid Gland in Patients With Systemic Sclerosis With and Without Hashimoto Thyroiditis
The study protocol Fifty patients with SSc according to the current international
classification will be included in the study. The patients, followed-up regularly in an
out-patient clinic, will be tested for their thyroid function tests as well as the presence
of thyroid auto antibodies. Clinical data will be collected from their medical records.
Ultrasonographic examination of the thyroid gland will be performed by a single examiner.
The gland will be characterized in detail with regards to its size and echotexture and
cervical lymph nodes will be detected. The number and size of its nodules will be described
as well as their echoic pattern (iso, hyperechoic or hypoechoic) calcifications (micro and
macro), and borders status. Large nodules (≥ 1 cm in diameter) or with malignancy-
associated characteristics will be aspirated according to current clinical practice.
Treatment will be given according to the cytology diagnosis. Thyroid hormone supplementation
will be recommended when thyrotropin level >8 mIU/L or according to clinical judgment of the
Observational Model: Cohort, Time Perspective: Prospective
There are no spesific outcome measures from trail
the measures from trail are equal to vast population
Pnina Rotman-Pikielny, MD
Meir Medical Center, Israel
Israel: Clalit Health Services