Inclusion Criteria:

- The patient or patient's legally authorized representative must sign and date the
Institutional Review Board approved Informed Consent and HIPPA Authorization Form.

- Male and female patients 18+ years of age with a clinical diagnosis of Tuberous
Sclerosis who experience an average of at least three partial seizures every two
months, of which one must be a complex partial seizure

- Patient must be on at least one and a maximum of four AEDs. Patient must be on a
stable AED dose regimen for at least 30 days prior to screening. Neither a Vagal
Nerve Stimulator (VNS) nor the ketogenic diet will count as an AED

- In the investigator's opinion, the patient or caregiver must be able to keep a
seizure diary

- An MRI in the last 5 years, or willingness to undergo an MRI as part of the screening
process

Exclusion Criteria:

- Cause of patient's seizures is a neurologic disease that is not Tuberous Sclerosis

- Current, clinical diagnosis of a major depressive episode or suicidal ideation

- Patient is taking more than four concurrent AEDs. Note: VNS or ketogenic diet is
allowed and will not be counted in the four allowed AEDs

- Patient has a progressive CNS lesion confirmed by magnetic resonance imaging (MRI) or
computed tomography (CT) scan

- Patient is currently abusing drugs or alcohol