Screening MRI for Cancer Recurrence in Patients Treated With Breast Conserving Therapy
- Patients treated with breast conserving therapy will be followed for recurrence in the
ipsilateral or contralateral breast by physical examination every six month and imaging
studies performed annually.
- The imaging including mammography, physician-performed bilateral whole breast
ultrasonography and a dynamic breast MRI with gadolinium-containing contrast medium
will be performed according to a standard protocol. Interpretation will be conducted
independently and classified according to the Breast Imaging Reporting and Data System
(BI-RADS) by experienced radiologists.
- Definitive information about the presence of malignancy will be obtained by biopsy
directed by the imaging method best depicting the lesion with 14-g or 11-g needle
devices or needle localized excision. The absence of breast cancer was determined by
means of biopsy, the absence of positive findings on repeat imaging and clinical
examination, or both at follow-up.
- After three rounds of annual screening, the diagnostic yield of screening MRI compared
to physical examination, mammography or ultrasonography will be assessed.
Observational Model: Case-Only, Time Perspective: Prospective
Diagnostic yield of screening breast MRI
Three years after the first screening MRI
Woo Kyung Moon, M.D., Ph.D.
Department of Radiology, Seoul National University Hospital
Korea: Ministry for Health, Welfare and Family Affairs
Screening MR for Recurred BrCa