The Tumour Bed as Target for Breast Irradiation Following Breast Conserving Surgery
Consenting patients who have undergone breast conserving surgery and who are planned to
receive radiotherapy will have their first MRI and CT scan within 2 weeks of treatment
planning. This will be followed by 3 weeks radiotherapy treatment. 3D ultrasound scans will
be performed in the first 2 weeks before radiotherapy, during the 2nd and 3rd weeks of
radiotherapy and in the 2 weeks following radiotherapy.Following the radiotherapy patients
will undergo both CT and MRI scans within 2 weeks of treatment completion.The whole process
should take approximately 10 weeks.In this study the CT scans, MRI scan + USS are above
standard care and are the additional interventions in this study group.
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label
Maximal dimensions of post operative complex will be obtained using the British Colombia Cancer Agency Seroma Clarity score scale.
Each modality of investigation i.e. CT, MRI +USS will be evaluated using the Seroma clarity score scale to determine the most useful investigational tool.
Within 3 months of radiotherapy completion
Amit K Bahl, MD,MRCP,FRCR
University Hospitals Bristol NHS Foundation Trust
United Kingdom: Research Ethics Committee